Handbook of pharmaceutical excipients /

Abstract

The Handbook of Pharmaceutical Excipients is a comprehensive reference work that provides detailed scientific information on excipients—the non‑active substances used in pharmaceutical formulations. Edited by Raymond C. Rowe and colleagues, this handbook is widely recognized as an industry and academic standard reference for formulation scientists, pharmacists, and regulatory professionals.

The book systematically describes the physical and chemical properties, functional uses, compatibilities, safety profiles, and regulatory status of excipients used in modern dosage forms. It integrates data from chemical, pharmaceutical, and toxicological sources to support the appropriate selection, evaluation, and application of excipients in tablets, capsules, liquids, semisolids, aerosols, and other dosage forms.

Each excipient monograph includes information on sources and grades, key characteristics (e.g., particle size, moisture content, pH), typical concentration ranges, formulation considerations, and potential interactions with active pharmaceutical ingredients (APIs). The handbook also guides quality control tests, stability, manufacturing processes, and regulatory classifications across major global pharmacopeias.

Overall, the handbook serves as a practical and scientific resource for formulation development, troubleshooting, regulatory submission, academic research, and quality assurance, helping practitioners to design safe, effective, and robust pharmaceutical products.